Friday, January 28, 2011

The Dark Side: WHEAT

Here is an extra LONG blog- WHEAT- it's whats killing us!

Wikipedia link -
Despite popular opinion wheat consumption may not be beneficial to health. These two published articles make a strong argument against perceiving wheat intolerance as simply a matter of allergy/genetic intolerance in a minority subset of the human population, but rather as a species-specific intolerance, applicable to all.
Part 1: The Dark Side of Wheat: New Perspectives on Celiac Disease & Wheat Intolerance
Part 2: Opening Pandora’s Bread Box: The Critical Role of Wheat Lectin in Human Disease.
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Associated Content
 - 102
 - 379
Quick Summary: Top Diseases for Wheat
NameEvidence DensityArticle Count
Celiac Disease22365
Gluten Intolerance14237
Wheat Intolerance12829
Gluten Sensitivity8627
Food Allergies: Wheat516
Psoriasis428
Schizophrenia4112
Dermatitis Herpetiformis404
Multiple Myeloma404
Sjogren's Syndrome404
Notice: Articles are Alphabetized According to Relevant Substances
Quick Access: Toxicological Articles
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Toxicological Articles

Wheat gluten may exert its adverse effects through activation of complement (a cascade of proteins in the blood that form part of innate immunity).

Study Type : Human Study
Additional Links:
Additional Keywords : Plant Extracts
Toxic Ingredients : Gluten

Gluten intolerance gives rise to a variety of dermatological manifestations which may benefit from a gluten-free diet.

Study Type : Commentary
Additional Links:
Toxic Ingredients : Gluten, Wheat

A novel wheat gliadin is the cause of exercise-induced anaphylaxis.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin

Rye and barley may elicit symptoms in patients with wheat-dependent, exercise-induced anaphylaxis.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Barley, Gliadin , Gluten, Grains, Rye

A large number of neurologic syndromes may result from gluten intolerance.

Study Type : Commentary
Additional Links:
Toxic Ingredients : Gluten

A high prevalence of gluten sensitivity is found in sporadic and hereditary cerebellar ataxia.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten
Adverse Pharmacological Actions : Neurotoxic

There is a weak but positive correlation with the presence of coronary heart disease and the presence of anti-gliadin antibodies.

Study Type : Human Study
Additional Links:
Additional Keywords : anti-gliadin antibodies
Toxic Ingredients : Gliadin , Wheat

A Gluten and casein-free diet may have a therapeutic effect in autism spectrum and attention deficit disorders.

Study Type : Human Study
Additional Links:
Additional Keywords : gluten and ADHD
Toxic Ingredients : Casein, Gluten

ADHD sympomatology is markedly over represented among untreated CD patients and that a gluten-free diet may improve symptoms significantly within a short period of time.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked, gluten and ADHD
Toxic Ingredients : Gluten

Wheat germ agglutinin (WGA) induces antibody anti-WGA formation, which may result in some cross-reactivity to other proteins.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Celiac disease is far higher in those diagnosed with Grave's disease.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten, Wheat

There is a higher prevalance of celiac disease and gluten sensitivity in patients with Grave's hyperthyroidism.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin

Wheat germ agglutinin (WGA) enters through the blood-brain-barrier through adsorptive endocytosis.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) enhances the passage of native horseradish peroxidase enzyme (HRP) approximately 10 times more rapidly than HRP alone.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) is used as a neural network tracer due to its ease of transit through the nervous system.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) lectin has neuromodulatory effects.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) has neuromodulatory effects - Article 2.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Hippocampal sclerosis in refractory temporal lobe epilepsy is associated with gluten sensitivity.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten

Plant sprouts within the Gramineae family such as wheat, maize and rye contain potentially carcinogenic compounds known as benzoxinoids (BAs).

Study Type : In Vitro Study
Additional Links:
Diseases : Cancers: All
Toxic Ingredients : Benzoxazinoids (BAs) , Corn, Grains, Rye, Wheat

Cardiomyopathy in patients with celiac disease may be completely reversible with a gluten-free diet.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Wheat

Neurological symptoms occur in 6-10% of those with celiac disease, with cerebella ataxia being the most frequent symptom.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gluten
Adverse Pharmacological Actions : Neurotoxic

A variety of foods contain opioid receptor ligands.

Study Type : Review
Additional Links:
Additional Keywords : food drugs
Toxic Ingredients : Casein, Gluten, Grains, Meat: Cooked

Highly significant increases compared with controls were found in patients with multiple sclerosis for IgA and IgG antibodies against gliadin and gluten and IgA antibodies against casein.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Casein, Gliadin , Gluten
Adverse Pharmacological Actions : Neurotoxic

Elevated IgA antibodies to gluten and gliadin proteins and to casein in milk have been found in patients with Rett syndrome.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Casein, Gliadin , Gluten

Review: prevalence of celiac disease in the Asia-Pacific region.

Study Type : Human Study
Additional Links:
Diseases : Celiac Disease
Toxic Ingredients : Wheat

Wheat lectin may be responsible for aggravating celiac disease through secondary intolerances, as well as the occurence of intestinal lesions in healthy subjects administered high levels of gluten.

Study Type : Commentary
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Dietary lectins may contribute to the pathogensis of celiac disease.

Study Type : Animal Study
Additional Links:
Diseases : Celiac Disease
Additional Keywords : Lectins

Wheat germ agglutinin (WGA) is cytotoxic toward several tissue culture lines.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) may be involved in the pathogenesis of celiac disease.

Study Type : Commentary
Additional Links:
Diseases : Celiac Disease
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) may be responsible for the crypt hyperplasia found in celiac children due to a mitogenic response induced by wheat germ agglutin (WGA).

Study Type : Commentary
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

The effect of gliadin on lymphocytes from patients with celiac disease may be mediated through opioid-like receptors.

Study Type : Commentary
Additional Links:
Diseases : Celiac Disease
Toxic Ingredients : Gliadin

Wheat gluten hydrolates demonstate high opioid-like activity.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : opioid-like activity
Toxic Ingredients : Gliadin , Gluten, Wheat

Wheat, rye, and barley proteins may act as aids to carcinogens.

Study Type : Commentary
Additional Links:
Toxic Ingredients : Barley, Gluten exorphins, Grains, Rye, Wheat

Celiac disease prevalance is significantly higher in those diagnosed with Sjogren's syndrome.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Wheat

There is a close association between Sjögren's syndrome and celiac disease. Even among nonceliac patients with primary Sjögren's syndrome, an ongoing inflammation is often present in the small bowel mucosa.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Wheat

There is an association between psoraisis and asymptomatic celiac disease/gluten intolerance.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Wheat

Gluten causes gastrointestinal symptoms in subjects without celiac disease.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten, Wheat

Patients with multiple myeloma have immunoreactivity to gliadin similar to those with celiac disease.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Wheat
Adverse Pharmacological Actions : Immunoreactive

Sensory ganglionopathy may be a manifestation of gluten sensitivity.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten
Adverse Pharmacological Actions : Neurotoxic

Myopathy associated with gluten sensitivity has been demonstrated.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten

Wheat gliadin exhibits non-specific cytotoxicity to a variety of human cells.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Gliadin
Adverse Pharmacological Actions : Cytotoxic

Primates exhibit gluten sensitivity.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten

A significant proportion of patients with migraine may have celiac disease, and that a gluten free diet may lead to a improvement in the migraine in these patients.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gluten, Wheat

Celiac disease and migraine disorders may be linked.

Study Type : Human: Case Report
Additional Links:
Diseases : Celiac Disease
Toxic Ingredients : Gluten, Wheat

There is a high prevlance of gluten sensitivity in Japanese patients with adult-onset cerebellar ataxia.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten, Wheat
Adverse Pharmacological Actions : Neurotoxic

Patients with psoriasis show elevated sensitivity to gluten.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Gluten

Markers of gluten sensitivity and celiac disease are increased in recent-onset psychosis and multi-episode schizophrenia.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten, Wheat
Adverse Pharmacological Actions : Neurotoxic

Individuals with schizophrenia have a novel immune response to gluten.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Gluten
Adverse Pharmacological Actions : Neurotoxic

Diarrhea-predominant irritable bowel syndrome is associated with celiac-disease associated serum IgG in 55% of the patients tested. A gluten-free diet results in significant improvements.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Gluten, Wheat

A subgroup of Irritable Bowel Syndrome patients have latent/potential celiac disease and respond to a gluten-free diet.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Gluten, Wheat

There is an increased frequency of gliadin antibodies in patients with Down syndrome, indicating the possibilty of an increased incidence of celiac disease in this population.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin

There is a prevalence of IgA-antigliadin antibodies and IgA-antiendomysium antibodies related to celiac disease in children with Down syndrome.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Wheat

The prevalence of celiac disease in Down syndrome in the southeastern United States was 1 in 14 cases.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin

There is a higher prevalence of celiac disease in patients with Down syndrome than background populations.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin

Adults with Type 1 diabetes have a higher prevalance of celiac disease associated antibodies.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin , Wheat

The prevalence rate of celiac disease in Libyan children with type 1 diabetes was 10.3%.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin

Celiac disease prevalance was found to be 3.5% in children with type 1 diabetes.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin

There is a high prevalance of antibodies to gliadin in patients with inflammatory myopathies, indicating a higher prevalance of gluten sensitivity or celiac disease in this patient group.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gliadin

Benign neuromyeltitis optica has been linked to celiac disease.

Study Type : Human: Case Report
Additional Links:
Toxic Ingredients : Wheat

Clinically pertinent coeliac disease exists despite normal small-bowel mucosal villous architecture.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten

Gluten sensitivity is associated with sporadic cerebellar ataxia in Taiwan.

Study Type : Human Study
Additional Links:
Diseases : Cerebellar Ataxia
Toxic Ingredients : Gluten
Adverse Pharmacological Actions : Neurotoxic

Patients with chronic liver disease have a high prevalence of anti-tTg antibodies, similar to patients with celiac disease.

Study Type : Human Study
Additional Links:
Additional Keywords : anti-endomysium antibodies, anti-tTG
Toxic Ingredients : Gliadin , Gluten, Wheat

Gliadorphin-7 and beta-casomorphin-7 are pharmacologically active food peptides.

Study Type : Animal Study
Additional Links:

Non-degraded gliadin can be found in high levels in the breast milk of healthy mothers.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Gliadin

Wheat and potato have pharmacologically active benzodiazepines in trace amounts.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Potato, Wheat

Wheat and potato have pharmacologically active benzodiazepines which increase during germination.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Potato, Wheat

A wheat-based diet enhances colonization with the intestinal spirochaete Brachyspira intermedia in experimentally infected laying hens.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Wheat

Wheat germ agglutinin (WGA) and concanavalin A (Con A) stimulate platelet aggregation.

Study Type : In Vitro Study
Additional Links:
Diseases : Clotting

Wheat germ agglutinin (WGA) levels are maintained in significant quantities for prolonged periods of time (34+ days) in sprouted wheat.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) has fungicidal properties and may function in the defense against fungal pathogens.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) activates human neutrophils.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) and concanavalin bind to peripheral nerve fibres such as myelin in an animal model.

Study Type : Animal Study
Additional Links:
Additional Keywords : Lectins

Wheat germ agglutinin (WGA) is capable of blocking the inhibitory effect of nerve growth factor, in vitro.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin blocks the biological effects of nerve growth factor.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) is capable of modifying nerve growth factor receptor properties.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ lectin exhibits cytotoxicity.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) and concanavalin A can interfere with and/or modulate cellular processes.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) has been shown to inhibit nuclear DNA replication and prevents transport into the cell nucleus.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) and concanavalin A have insulin-like activity.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : insulin mimetic

Patients with dermatitis herpetiformis have serum antibodies to wheat germ agglutinin and gluten.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten, Wheat Germ Agglutinin (WGA)

Patients with dermatitis herpetiformis have antibodies to gliadin which may cross-react with dermal reticulin.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin

Wheat gluten hydrolates demonstate high opioid-like activity.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : opioid-like activity
Toxic Ingredients : Gliadin , Gluten, Wheat

The habitual consumption of wheat gluten may be a contributing factor in the pathogenesis of type 1 diabetes.

Study Type : Commentary
Additional Links:
Additional Keywords : zonulin
Toxic Ingredients : Gliadin , Gluten, Wheat

A casein- and wheat-free diet was associated with the lowest rate of autoimmune diabetes (type 1) development in mice.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Casein, Gluten
Adverse Pharmacological Actions : Diabetogenic

Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Barley, Gliadin , Gluten, Grains, Wheat
Adverse Pharmacological Actions : Diabetogenic

Gluten encephalopathy with psychiatric onset has been reported.

Study Type : Human: Case Report
Additional Links:
Toxic Ingredients : Gluten, Wheat
Adverse Pharmacological Actions : Neurotoxic

Gliadin and alcohol may contribute to igA nephropathy.

Study Type : Animal Study
Additional Links:
Diseases : Food Allergies
Toxic Ingredients : Ethanol, Gliadin , Wheat

Wheat gliadin may promote its pro-allergenic effects by upregulation of interleukin-4 induced IgE production.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Gliadin
Adverse Pharmacological Actions : Allergenic, Inflammatory, Interleukin-4 Up-regulation

Ochratoxin A contamination poses a risk in wheat and corn bread.

Study Type : Review
Additional Links:
Diseases : Food Poisoning
Toxic Ingredients : Corn, Ochratoxin A , Wheat

Wheat lectin exhibits inflammatory and permeability-inducing effects on the human gastrointestinal lining at nanomolar concentrations via the stimulation of immune cells.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) and the antibiotic monesin work synergistically to induce cytotoxicity.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Monensin, Wheat Germ Agglutinin (WGA)

Wheat lectin may be responsible for contributing to intestinal disease.

Study Type : Animal Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Gluten sensivity may not be detectable with conventional light microscopy.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten

Gluten and its lectin-like fraction gliadin contribute to experimental IgA glumerulopathy.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten, Wheat

Schizophrenia prevalence is correlated with gluten grain consumption.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gluten, Gluten exorphins

Palmoplantar pustulosis is a condition highly correlated to gluten sensitivity.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Wheat

A Gluten-free diet in psoriasis patients with antibodies to gliadin results in significant clinical improvements.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Wheat

Gliadorphin-7 and beta-casomorphin-7 are pharmacologically active food peptides.

Study Type : Animal Study
Additional Links:

Persons with schizophrenia have higher than expected titers of antibodies related to celiac disease and gluten sensitivity.

Study Type : Human Study
Additional Links:
Additional Keywords : diseases that are linked
Toxic Ingredients : Gluten, Wheat
Adverse Pharmacological Actions : Neurotoxic

Gluten sensitivity is prevalent in patients with IgA nephropathy.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin
Adverse Pharmacological Actions : Renotoxic

Gluten sensitivity is a clinically confirmed problem in multiple sclerosis.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Gluten
Adverse Pharmacological Actions : Neurotoxic

Gluten exorphin B5 enhances prolactin secretion in male rats.

Study Type : Animal Study
Additional Links:
Additional Keywords : Exorphin B5
Toxic Ingredients : Gluten

Wheat germ agglutinin (WGA) and concanavalin A exhibit insulin-mimetic properties.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : insulin mimetic

A gluten-free diet improves primary IgA nephropathy in 75% of patients.

Study Type : Human Study
Additional Links:
Diseases : IgA Nephropathy
Toxic Ingredients : Gluten, Wheat

Gluten exorphin modulate pancreatic endocrine function by stimulating inuslin release.

Study Type : Animal Study
Additional Links:
Toxic Ingredients : Gluten exorphins
Adverse Pharmacological Actions : Endocrine Disruptor: Pancreas

Gliadin activates zonulin signaling irrespective of the genetic expression of autoimmunity, leading to increased intestinal permeability to macromolecules.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : zonulin
Toxic Ingredients : Gliadin

Gliadin induces an increase in intestinal permeability.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : zonulin
Toxic Ingredients : Gliadin

Gliadin induces an increase in intestinal permeability - Article 2.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : zonulin
Toxic Ingredients : Gliadin

Gliadin causes intestinal permeability in both celiac and non-celiac intestinal mucosa.

Study Type : Human Study
Additional Links:
Additional Keywords : zonulin
Toxic Ingredients : Gliadin

The risk of renal cell carcinoma is associated with bread, pasta, rice, milk and yoghurt consumption.

Study Type : Human Study
Additional Links:
Diseases : Kidney Cancer

Bread and pasta consumption (two main sources of wheat) are associated with increased risk for kidney cancer.

Study Type : Human Study
Additional Links:
Diseases : Kidney Cancer
Toxic Ingredients : Wheat

Wheat germ agglutinin (WGA) exhibits activity in a plasma membrane preparation of rat pancreas, which can be blocked by a n-acetyl-d-glucosamine rich glyoprotein.

Study Type : Animal Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) exhibits anti-nutritive properties, e.g. hypertrophic growth of the pancreas and thymus atrophy.

Study Type : Animal Study
Additional Links:
Additional Keywords : Lectins, lectins as insecticides
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) and pertussis toxin are molecularly homologous.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins, molecular mimicry
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Gluten exorphins alter serum prolactin levels in male rats.

Study Type : Animal Study
Additional Links:
Additional Keywords : food drugs
Toxic Ingredients : Gluten, Gluten exorphins
Adverse Pharmacological Actions : Endocrine Disruptor

Multiple myeloma patients exhibit humoral immunoreactivity to gliadin and to tissue transglutaminase, not unlike those with celiac disease.

Study Type : Human Study
Additional Links:
Toxic Ingredients : Gliadin , Wheat
Adverse Pharmacological Actions : Immunoreactive

Wheat gluten contains opioid peptides.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : food drugs, opioid-like activity
Toxic Ingredients : Gluten, Gluten exorphins, Wheat

Wheat gluten contains a novel opioid peptide named gluten exorphin C.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : opioid-like activity
Toxic Ingredients : Gluten, Gluten exorphins, Wheat

Gastrointestinal proteases break down wheat gluten resulting in the release of opioid peptides.

Study Type : Animal Study
Additional Links:
Additional Keywords : opioid-like activity
Toxic Ingredients : Gluten, Gluten exorphins, Wheat

Lectins bind to inflamed synovial tissue of patients with osteoarthritis and rheumatoid arthritis.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Opioid peptides derived from wheat gluten has an effect on pituitary function when administered intraperitoneally.

Study Type : Animal Study
Additional Links:
Diseases : Pituitary Diseases
Toxic Ingredients : Gluten, Gluten exorphins, Wheat

Gluten restriction shows promise in the treatment of schizophrenia.

Study Type : Human Study
Additional Links:
Diseases : Schizophrenia
Toxic Ingredients : Gluten

Wheat gluten may be a pathogenic factor in schizophrenia.

Study Type : Human Study
Additional Links:
Diseases : Schizophrenia
Toxic Ingredients : Gluten

Gluten grain consumption may be correlated with the risk for schizophrenia.

Study Type : Commentary
Additional Links:
Diseases : Schizophrenia
Toxic Ingredients : Gluten, Grains

Wheat germ agglutinin (WGA) and concanavalin A bind to benign and malignant thyroid nodules.

Study Type : Human Study
Additional Links:
Additional Keywords : Lectins

Wheat germ agglutinin (WGA) interacts with human platelets as an aggregator via fibrinogen receptors.

Study Type : In Vitro Study
Additional Links:
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) interacts with human platelets as an aggregator and agglutinizer.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) is a very potent platelet stimulator.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : Lectins
Toxic Ingredients : Lectins, Wheat Germ Agglutinin (WGA)

Wheat germ agglutinin (WGA) decreases levels of stress protein in rat gut and enterocyte-like Caco-2-cells, leaving these cells less well protected against the potentially harmful content of the gut lumen.

Study Type : In Vitro Study
Additional Links:

Wheat gliadin components exhibit cytotoxicity to a number of human cell lines.

Study Type : In Vitro Study
Additional Links:
Diseases : Wheat Intolerance
Additional Keywords : Lectins
Toxic Ingredients : Gliadin , Gluten, Wheat

Wheat gluten hydrolates demonstate high opioid-like activity.

Study Type : In Vitro Study
Additional Links:
Additional Keywords : opioid-like activity
Toxic Ingredients : Gliadin , Gluten, Wheathttp://www.greenmedinfo.com/toxic-ingredient/wheat
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